Save on Nature's Three and LOCLO - March 16-31
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posted by Karen Herrmann-DeSantis, Herb Specialist, Natural Health Educator | 11:28 PM
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A growing body of evidence suggests that all the antibacterial-wiping, germ-killing cleanliness of the developed world may actually be making us more prone to getting sick and that a little more dirt might help us stay healthier in the long run.
The idea, known as the hygiene hypothesis, was first proposed in 1989 by epidemiologist David P. Strachen, who analyzed data from 17,414 British children and found that those who had grown up with more siblings (and presumably more germs) were less likely to have allergies and eczema. Since then, the theory has been cited as a possible explanation for everything from multiple sclerosis to hay fever and autism. But its particulars aren't so clean and clear.
Here's what researchers do know: Our immune systems need bugs. They rely on early encounters with germs to learn how to protect our bodies.
"Bacteria, fungi, lots of these things we think of as bad they're all part of our environment, and we evolved to live with them," says Michael Zasloff, an immunologist and physician at Georgetown University Medical Center. Through exposure to these microbes early in life, your immune system learns what's harmful and what isn't, he says, and that readies the immune responses you'll have for the rest of your life.
"The body has got to know friend from foe," Zasloff says. If your body learns that a specific microbe or substance any antigen, or visitor to the body is a foe, it will send immune system cells to destroy it. If it recognizes the antigen as a friend, the immune system will leave it alone. "Exposure tells the immune system, 'These are the things you're going to run into all the time, so you don't need to worry about them.' "
According to the hygiene hypothesis, bad things can happen if this early exposure doesn't take place or if it doesn't include the right microbes. The immune system can become overly sensitive, overreacting to non-threats such as pollen or dander as if they're potentially harmful. When combined with certain genetic traits, this process can lead to conditions such as asthma and allergies, says Kathleen Barnes, an immunogeneticist at Johns Hopkins University who specializes in the genetics of asthma.
Barnes's work has revealed that although genes play a key role in the development of asthma, changing a population's exposure to microbes by protecting them from parasitic diseases, for example can make asthma rates rise. That suggests that hygiene may also play a role in asthma.
"It can't all be due to genes, because if we look at the prevalence of asthma or diseases of inflammation over the past 50 years, we see it's definitely on the rise," Barnes says. "It's some interaction between the genes and the environment that's causing these rates to skyrocket."
But researchers can't say which particular interactions with the environment help prevent disease later on. That's because exposures tend to come in combinations, and teasing apart their effects on the body is difficult.
Take farming, for instance. Several studies have suggested that growing up on a farm can protect children from allergies and other immune-system-related conditions, but it's hard to know which element of farm living does the trick.
A 2012 study of Amish and Swiss farm and non-farm children found that the farm-dwelling kids had significantly lower rates of asthma, hay fever and eczema. But the farm dwellers differed from their non-farm peers in several ways: They had more exposure to livestock and the microbes that come with them; they were more likely to drink raw milk, which contains microbes not found in pasteurized milk; and they tended to have more siblings at home.
Because each of these factors has been associated with reduced risk of allergies and related diseases, researchers can't pinpoint which factor or combination of factors provides the protection.
Parasites and disease-causing microbes have also shown a protective effect, but again it's not clear which microbes are doing the protecting. A 2007 study that compared genetically related children living in Finland and Russia found that the Russian children who were less wealthy than their Finnish counterparts and who more frequently showed antibodies to the hepatitis A virus, H. pylori bacteria and other microbes associated with poor hygiene practices were far less likely to have allergies. The findings made it clear that microbial infections and environmental differences were conferring an advantage, but they were less conclusive about which infections conferred the greatest advantage.
So what does all this mean? Should we ditch spring cleaning and adopt a dairy cow or a parasite to keep allergies at bay?
Probably not, says Barnes: Modern hygiene saves lives and prevents the spread of disease, and no researcher would advocate abandoning it entirely. But we may want to rethink our relationship with germs, she says.
"Knowing what I know about the hygiene hypothesis, I think twice before I run to a physician for an antibiotic," she says. "I also think about the foods my family eats. We eat a lot of yogurt for the beneficial bacterial cultures it provides."
Zasloff goes even further. He doesn't mind if his kids eat a little dirt, don't wash their hands before every meal or wear the same socks twice. Eating food that's been in the fridge a while or that has fallen on the floor is okay, too, he says.
That may not be for you. The important thing, Zasloff says, is moderation: "It's not that you should expose yourself to things that are going to kill you. We're just talking about living in a more microbially rich environment. That means you don't need to use antibacterial soaps or wipes, or clean everything with bleach, or even wash your clothes every day. Getting dirty isn't so bad. . . . Just use your common sense."
Article from the WashingtonPost.com
