Paw Paw Cell-Reg for Cancer - Protocol by Richard Lund
These are general recommendations for using Paw Paw Cell-Reg. This program was shared by Richard Lund on the nspadvisor Yahoogroup.
Because people who take it may have significantly different needs, it is wise to seek counsel of a trusted herbalist or your physician before using any herbal program. In other words, while this protocol may be right for many people, it may not be right for you.
Paw Paw Cell-Reg
Take one capsule with food four times a day. The target body weight for this amount is based on a person who weighs 150-170 pounds. People who weigh more may wish to take one or more additional capsules. Some people who weigh less may find it necessary to only use three per day. If you experience significant nausea or vomiting, reduce the amount that you take.
Ginger root sliced and boiled for ten minutes in a cup or two of water is a soothing tea that may help nausea if you experience it. Paw Paw Cell-Reg may be mixed with food by opening the capsules. Do not mix with hot liquids because it is sensitive to heat.
Protease Plus
Start by taking one capsule three times a day apart from food. Do it one hour before or two hours after meals. Build up to taking three capsules three times a day.
Immune Stimulator
Take ten to twenty capsules per day. These should be spread out through the day where possible. To get the maximum benefit from the ingredient colostrum, take Immune Stimulator apart from meals and apart from Protease Plus. If you are also taking Protease Plus, it may be very inconvenient to take that way. If this is too hard, take them with your meals. The mushroom ingredients and the arabinogalactan will not be affected. Immune Stimulator may be mixed with hot water to make an herbal tea. This may be mixed with licorice root (root slice, powdered, or a liquid) to make it more palatable. This sometimes is helpful for those who take "too many pills."
While we do not have direct clinical studies to support these recommendations, we believe that some food supplements may slow down the effectiveness of paw paw's active ingredients in the body. These fall into three categories.
The first are direct thyroid stimulants, such as iodine found in kelp. This molecule has a stimulatory function on mitochondrial metabolism at the same place that paw paw's acetogenins are acting to inhibit. People frequently take a supplement like kelp to supply minerals to the body or to trigger weight loss. Normal thyroid support prescriptions such as Armour thyroid or Synthroid® should be continued and only changed at the direction of a physician. If you have questions, be sure to ask your doctor.
The second thing to consider avoiding is CO-Q10. This is a form of ubiquinone, a molecule used as a co-enzyme electron carrier in the NADH ubiquinone oxidoreductase reaction that the acetogenins are trying to inhibit in complex one of the mitochondrial inner membrane. People sometimes take this supplement to help support their heart. Careful consideration of the benefits must be made before discontinuing such supplementation for heart health. Ask your doctor if you have concerns about its absence in your diet before changing. Normally the body makes this molecule, so it may not need to be supplemented in all people.
The third type of supplement to avoid is in the class of the antioxidants. Specific antioxidants that have an effect on the work of paw paw's acetogenins are Vitamin C, Vitamin E, N Acetyl Cysteine, and Glutathione. Some research supports my concerns about adding these as food supplements. Dr. McLaughlin recommends only using amounts of Vitamins A, C, and E that are recommended as daily requirements. So using an ordinary multiple vitamin may be suitable. Check the label for amounts of the RDA.
Some researchers advocate very high levels of Vitamin C intake to fight cancer. Often people who are under the care of specific oncologists have received up to 50 grams of Vitamin C daily. They believe that in large doses, the Vitamin C acts as an oxidizer, triggering apoptosis, instead of as an antioxidant, rescuing cancer cells from apoptosis. Certainly more study is needed to understand the chemistry of Vitamin C and its influences on disease conditions. Or perhaps, those who do understand its work need to help those of us outside of the world of research to understand it better. If your doctor tells you to take Vitamin C, let him guide you here.
Garlic may also be avoided generally with using paw paw. Another is selenium. SOD should be avoided as well. Some other supplements such as Noni and Mangosteen-based products (e.g. Thai-Go) have high antioxidant values and probably should be avoided unless taken for very specific needs. Balancing an herbal supplement program sometimes requires a personal knowledge of specific conditions and can be best accomplished by consultation with a knowledgeable person, such as an herbalist, acupuncturist, a naturopathic physician, an osteopath, a medical doctor, a pharmacist, or other qualified medical professional. Previously I had voiced concern over all true teas. Preliminary findings of a researcher from Detroit indicate that green tea may not inhibit paw paw, which would be good news. I will post more about this when I am able to discuss it with Dr. McLaughlin and upon his review of the test.
One supplement that we previously voiced concern about using with paw paw was IP-6 (also known as inositol hexaphosphate or phytic acid.) Recently I found the journal article that explains its antioxidant activity and was able to discuss phytic acid with one of the authors. Dr. Ernst Graf told me in personal conversation that he did not expect phytic acid to be active with hydrogen peroxide in the inner membrane of the mitochodria for two reasons. One is that the charge on the molecule because of the phosphate groups would probably not allow it to enter, and secondly that the main reaction phytic acid has as an antioxidant is to reduce ferrous iron. So we feel free to endorse its use with paw paw. It is found in many food supplements as an ingredient as well as a stand-alone product. It is available naturally in sesame seeds, brown rice, and corn, according to my reading.
Article written by Richard Lund (rlund@pawpawforhealth.com)
Because people who take it may have significantly different needs, it is wise to seek counsel of a trusted herbalist or your physician before using any herbal program. In other words, while this protocol may be right for many people, it may not be right for you.
Paw Paw Cell-Reg
Take one capsule with food four times a day. The target body weight for this amount is based on a person who weighs 150-170 pounds. People who weigh more may wish to take one or more additional capsules. Some people who weigh less may find it necessary to only use three per day. If you experience significant nausea or vomiting, reduce the amount that you take.
Ginger root sliced and boiled for ten minutes in a cup or two of water is a soothing tea that may help nausea if you experience it. Paw Paw Cell-Reg may be mixed with food by opening the capsules. Do not mix with hot liquids because it is sensitive to heat.
Protease Plus
Start by taking one capsule three times a day apart from food. Do it one hour before or two hours after meals. Build up to taking three capsules three times a day.
Immune Stimulator
Take ten to twenty capsules per day. These should be spread out through the day where possible. To get the maximum benefit from the ingredient colostrum, take Immune Stimulator apart from meals and apart from Protease Plus. If you are also taking Protease Plus, it may be very inconvenient to take that way. If this is too hard, take them with your meals. The mushroom ingredients and the arabinogalactan will not be affected. Immune Stimulator may be mixed with hot water to make an herbal tea. This may be mixed with licorice root (root slice, powdered, or a liquid) to make it more palatable. This sometimes is helpful for those who take "too many pills."
While we do not have direct clinical studies to support these recommendations, we believe that some food supplements may slow down the effectiveness of paw paw's active ingredients in the body. These fall into three categories.
The first are direct thyroid stimulants, such as iodine found in kelp. This molecule has a stimulatory function on mitochondrial metabolism at the same place that paw paw's acetogenins are acting to inhibit. People frequently take a supplement like kelp to supply minerals to the body or to trigger weight loss. Normal thyroid support prescriptions such as Armour thyroid or Synthroid® should be continued and only changed at the direction of a physician. If you have questions, be sure to ask your doctor.
The second thing to consider avoiding is CO-Q10. This is a form of ubiquinone, a molecule used as a co-enzyme electron carrier in the NADH ubiquinone oxidoreductase reaction that the acetogenins are trying to inhibit in complex one of the mitochondrial inner membrane. People sometimes take this supplement to help support their heart. Careful consideration of the benefits must be made before discontinuing such supplementation for heart health. Ask your doctor if you have concerns about its absence in your diet before changing. Normally the body makes this molecule, so it may not need to be supplemented in all people.
The third type of supplement to avoid is in the class of the antioxidants. Specific antioxidants that have an effect on the work of paw paw's acetogenins are Vitamin C, Vitamin E, N Acetyl Cysteine, and Glutathione. Some research supports my concerns about adding these as food supplements. Dr. McLaughlin recommends only using amounts of Vitamins A, C, and E that are recommended as daily requirements. So using an ordinary multiple vitamin may be suitable. Check the label for amounts of the RDA.
Some researchers advocate very high levels of Vitamin C intake to fight cancer. Often people who are under the care of specific oncologists have received up to 50 grams of Vitamin C daily. They believe that in large doses, the Vitamin C acts as an oxidizer, triggering apoptosis, instead of as an antioxidant, rescuing cancer cells from apoptosis. Certainly more study is needed to understand the chemistry of Vitamin C and its influences on disease conditions. Or perhaps, those who do understand its work need to help those of us outside of the world of research to understand it better. If your doctor tells you to take Vitamin C, let him guide you here.
Garlic may also be avoided generally with using paw paw. Another is selenium. SOD should be avoided as well. Some other supplements such as Noni and Mangosteen-based products (e.g. Thai-Go) have high antioxidant values and probably should be avoided unless taken for very specific needs. Balancing an herbal supplement program sometimes requires a personal knowledge of specific conditions and can be best accomplished by consultation with a knowledgeable person, such as an herbalist, acupuncturist, a naturopathic physician, an osteopath, a medical doctor, a pharmacist, or other qualified medical professional. Previously I had voiced concern over all true teas. Preliminary findings of a researcher from Detroit indicate that green tea may not inhibit paw paw, which would be good news. I will post more about this when I am able to discuss it with Dr. McLaughlin and upon his review of the test.
One supplement that we previously voiced concern about using with paw paw was IP-6 (also known as inositol hexaphosphate or phytic acid.) Recently I found the journal article that explains its antioxidant activity and was able to discuss phytic acid with one of the authors. Dr. Ernst Graf told me in personal conversation that he did not expect phytic acid to be active with hydrogen peroxide in the inner membrane of the mitochodria for two reasons. One is that the charge on the molecule because of the phosphate groups would probably not allow it to enter, and secondly that the main reaction phytic acid has as an antioxidant is to reduce ferrous iron. So we feel free to endorse its use with paw paw. It is found in many food supplements as an ingredient as well as a stand-alone product. It is available naturally in sesame seeds, brown rice, and corn, according to my reading.
Article written by Richard Lund (rlund@pawpawforhealth.com)
posted by Karen Herrmann-DeSantis, Herb Specialist, Natural Health Educator | 10:29 AM
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